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Tramadol

September 23rd 2006 23:25
Tramadol :
Tramadol is used for the treatment of moderate to moderately severe pain. It acts on the central nervous system (brain and spinal cord) to relieve pain. The mechanism of action of tramadol is not related to any other analgesics. The mechanism of action is poorly understood.
Treatment :
Tramadol should be taken every four to six hours as needed
for pain (unless your doctor specifically instructs you to do otherwise). It can be taken with food or on an empty stomach.

Tramadol works most effectively if you take it at the onset of pain, rather than waiting until the pain becomes intense.


If you are taking tramadol on a schedule and you miss a scheduled dose, take the missed dose as soon as possible. However, if it is almost time for your next dose, do not take
the missed dose at all; just return to your regular schedule.
Do not double the next dose unless your doctor directs you
to do so.

Side Effects :
Minor: Constipation, diarrhea, dizziness, dry mouth, fatigue, itching, nausea or vomiting, nervousness, restlessness, sleep disorders, sweating, or upset stomach. These side effects should disappear as your body adjusts to tramadol.

Dry mouth can be relieved by sucking on ice chips or a piece of hard candy or by chewing sugarless gum.

If you feel dizzy or light-headed, sit or lie down for a while; get up from a sitting or lying position slowly; and be careful on stairs.

To avoid dizziness when you stand, contract and relax the muscles of your legs for a few moments before rising. Do this by pressing one foot against the floor while raising the other foot slightly, alternating feet so that you are "pumping" your legs in a pedaling motion.

To prevent constipation, increase the amount of fiber in your diet (fresh fruits and vegetables, salads, bran, whole-grain breads), exercise, and drink more water (unless your doctor tells you not to do so).


Major: Tell your doctor about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about black, tarry stools; chest tightness; difficulty urinating; hallucinations; headaches; loss of coordination; mental depression; palpitations; rash; seizures; tremors; or trouble breathing.

Interactions :
Tramadol interacts with several other types of medications:

Use of tramadol within 14 days of a monoamine oxidase (MAO) inhibitor (isocarboxazid, furazolidone, pargyline, phenelzine, procarbazine, or tranylcypromine) can result in high blood pressure along with other side effects.


Tramadol may increase the sedative effects of alcohol or other drugs that interact with central nervous system action (such as anesthetic medications, opioids, phenothiazines, sedative hypnotics, or tranquilizers).


Tramadol may increase the risk of seizures in patients with epilepsy or in those patients that receive medications that may increase the risk of seizure (medications such as MAO inhibitors and neuroleptics).


Higher doses of tramadol may be necessary in patients who are also taking carbamazepine.


Tramadol may increase your chances of having side effects from certain antidepressants. Discuss this with your doctor or pharmacist.
BE SURE TO TELL YOUR DOCTOR about any medications you are currently taking, especially any listed above.

Warnings :
Tell your doctor about any unusual or allergic reactions you have had to any medications, especially to tramadol or to other analgesics.


Before having surgery or other medical or dental procedures, tell your doctor or dentist that you are taking tramadol.


Tell your doctor if you have a history of drug abuse or if you have or ever had abdominal disease, peptic ulcers, epilepsy, head injuries, heart disease, kidney disease, or liver disease.


Tramadol can cause drowsiness or dizziness. Your ability to perform tasks that require alertness, such as driving an automobile or operating potentially dangerous machinery, may be decreased. Caution is required.


Do not drink any alcohol while you are being treated with tramadol.


Be sure to tell your doctor if you are pregnant. Although extensive studies in human pregnancy have not been conducted, tramadol has been shown to cause side effects in the fetuses of animals that received large doses of the drug during pregnancy. Tramadol is known to cross the placenta. Also tell your doctor if you are nursing an infant. It is not known if tramadol passes into breast milk
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