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Gatifloxacin and working

December 4th 2006 14:04
Gatifloxacin and working :
Gatifloxacin is an antibiotic that is used to treat a wide variety of bacterial infections, including pneumonia, urinary tract infections, sinusitis, and acute attacks of bronchitis. It acts by severely injuring the cell walls of infecting bacteria, preventing them from growing and multiplying. This medication kills susceptible bacteria, but it is not effective against viruses, parasites, or fungi.

Gatifloxacin Facts
Brand name (manufacturer): Tequin (Bristol-Myers Squibb)

Type of drug: Quinolone antibiotic

Ingredient: Gatifloxacin


Dosage form: Tablets (200 mg and 400 mg)

Storage: Store at room temperature in a tightly closed container.

Treatment :
Take gatifloxacin exactly as prescribed by your doctor -- usually for 7 to 14 days -- even if your symptoms improve. If you stop taking this medication too soon, resistant bacteria are given a chance to continue growing, and the infection could recur.

Gatifloxacin may be taken with food or on an empty stomach. Drink several additional glasses of water every day when you are taking this medication, unless your doctor tells you otherwise. Drinking water will help to prevent unwanted effects from this medication.

It is very important that you do not miss a dose of gatifloxacin. If you miss a dose of this medication, take the missed dose immediately. However, if you do not remember to take the missed dose until it is almost time for your next dose, take it and space the following dose halfway through the regular interval between doses; then return to your regular dosing schedule. It is important that you try not to skip any doses of this medication.

Side Effects :
Minor: Abdominal pain, diarrhea, dizziness, insomnia, light-headedness, nausea, or vomiting. These side effects usually go away during treatment, as your body adjusts to the medicine.


Gatifloxacin may increase your sensitivity to sunlight. Be cautious during exposure to the sun. Use an effective sunscreen and avoid exposure to sunlamps.

To avoid dizziness or light-headedness when you stand, contract and relax the muscles of your legs for a few moments before rising.

If you feel dizzy or light-headed, sit or lie down for a while. Get up slowly from a sitting or lying position, and be careful on stairs.

Major: Notify your doctor if any side effects are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about agitation, change in your vision, confusion, difficulty breathing, difficulty urinating, headache, muscle or joint pain, restlessness, severe diarrhea (which can be watery or contain pus or blood), skin rash, or swelling of the face. If your symptoms of infection seem to be getting worse rather than improving, contact your doctor immediately.

Interactions :
Gatifloxacin interacts with a number of other medications:

Antacids with aluminum or magnesium, vitamins with iron, or sucralfate should not be taken within four hours after taking gatifloxacin, since these medications may reduce the effectiveness of gatifloxacin.


Gatifloxacin should not be taken with quinidine, procainamide, amiodarone, or sotalol. These medications may increase the risk of side effects on the heart.


The effects of phenytoin may be reduced if given together with gatifloxacin, increasing the risk of having a seizure.


Regular consumption of large quantities of caffeine-containing beverages, such as coffee, tea, or colas, with this medication may lead to exaggerated or prolonged effects of caffeine. Your doctor may ask you to restrict your intake of caffeine during therapy with this medication.


Gatifloxacin may increase the actions and adverse effects of warfarin, cyclosporine, digoxin, and theophylline.


Probenecid can increase the blood levels and adverse effects of gatifloxacin.
BE SURE TO TELL YOUR DOCTOR if you are already taking any of the medications listed above or about any other medications you are taking.

Warnings :
It is important to tell your doctor if you have ever had any unusual or allergic reaction to gatifloxacin, any other quinolone antibiotic (including ciprofloxacin, levofloxacin, ofloxacin, sparfloxacin, enoxacin, norfloxacin, cinoxacin, or nalidixic acid), or any other medication.


It is important to tell your doctor if you now have or ever had brain or spinal cord disease, epilepsy, kidney disease, or liver disease.


To decrease the potential for harmful effects on your kidneys, increase your intake of fluids (nonalcoholic) unless your doctor directs you to do otherwise.


If you are having surgery or undergoing any type of dental procedure, be sure to tell your doctor or dentist that you are taking gatifloxacin.


While taking gatifloxacin, your ability to perform tasks that require alertness, such as driving a car or operating potentially dangerous machinery, may be impaired.


Gatifloxacin has been prescribed for your current infection only. Another infection later on, or one that someone else has, may require a different medicine. You should not give your medication to other people or use it for other infections, unless your doctor specifically directs you to do so.


Be sure to call your doctor immediately if you experience rash, swelling of the face, or difficulty breathing after you take this medication.


Gatifloxacin should not be used in young children.


Be sure to tell your doctor if you are pregnant. This medication and other quinolone antibiotics have been shown to cause serious adverse effects in the developing fetus. Also tell your doctor if you are breast-feeding an infant. This medication may pass into breast milk and should not be taken by a nursing mother.

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