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Efavirenz and working

November 11th 2006 03:27
Efavirenz :
Efavirenz is used in the treatment of human immunodeficiency virus (HIV) infection. HIV is the virus that causes AIDS. Efavirenz works by inhibiting the reproduction, or growth, of the virus, which slows down the progression of AIDS. Efavirenz does not cure HIV infection or AIDS, but it may delay the onset of other infections and diseases caused by AIDS.

Treatment :
Efavirenz works best when the level of medicine in your bloodstream is kept constant. It is best to take the drug at evenly spaced intervals throughout the day. To avoid stomach irritation, you can take efavirenz with food or with a full glass of water (unless your doctor tells you to do otherwise). However, efavirenz should NOT be taken with a high-fat meal. Bedtime dosing is often recommended.



Side Effects :
Minor: Abnormal dreams, diarrhea, difficulty concentrating, dizziness, headache, insomnia, muscle aches or pains, nausea, rash, or vomiting. These side effects should diminish or disappear as your body adjusts to the medication.


Major: Tell your doctor about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about anxiety, changes in the position or location of body fat, confusion, drowsiness, hallucinations, mood changes, severe skin rash with blistering or fever, or yellowing of the skin or the eyes


Interactions :
Efavirenz may interact with a number of medications.

Concurrent use of alcohol or other central nervous system depressants (antihistamines, barbiturates, benzodiazepines, muscle relaxants, or antidepressants) with efavirenz may cause extreme drowsiness.

Efavirenz should never be taken with benzodiazepines (including diazepam, midazolam, and triazolam), voriconazole, or ergot derivatives, since these combinations may cause life-threatening reactions.


Warnings :
Tell your doctor if you have ever had an allergic reaction to efavirenz or to any other medication.

Before taking this medication, be sure to tell your doctor about any medical problems you may have, especially a history of drug abuse, mental illness, or liver disease.

Tell your doctor immediately if you notice any type of skin rash, especially if it is severe or if it is accompanied by blisters or fever.


If efavirenz makes you dizzy or drowsy, do not participate in any activity that requires alertness, such as driving a car or operating potentially dangerous equipment.
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