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Diphenhydramine

November 10th 2006 02:44
Treatment :
To avoid stomach upset, take diphenhydramine with food, milk, or water (unless your doctor directs you otherwise).

Measure the elixir and syrup carefully with a specially designed 5-mL measuring spoon. An ordinary teaspoon is not accurate enough for medical purposes.

If you miss a dose of diphenhydramine, take the missed dose as soon as possible. However, if it is almost time for your next dose, do not take the missed dose at all; just return to your regular dosing schedule. Do not double the next dose.

Side Effects :
Minor: Blurred vision; confusion; constipation; diarrhea; dizziness; dry mouth, throat, or nose; headache; irritability; loss of appetite; nausea; restlessness; stomach upset; or unusual increase in sweating. These side effects should disappear as your body adjusts to the medication.


Major: Tell your doctor about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about changes in menstruation, clumsiness, difficult or painful urination, feeling faint, flushing of the face, hallucinations, palpitations, rash, ringing or buzzing in the ears, seizures, shortness of breath, sleeping disorders, sore throat or fever, tightness in the chest, unusual bleeding or bruising, or unusual tiredness or weakness.

Diphenhydramine belongs to a group of drugs known as antihistamines. (Antihistamines block the action of histamine, a chemical that is released by the body during an allergic reaction.) It is therefore used to treat or prevent symptoms of allergy. Diphenhydramine is also used to treat motion sickness and Parkinson's disease, as a nighttime sleeping aid, and as a nonnarcotic cough suppressant.

Interactions :

Diphenhydramine interacts with several other types of medications:

Concurrent use of diphenhydramine with other central nervous system depressants (for example, alcohol, barbiturates, benzodiazepine tranquilizers, muscle relaxants, narcotics, pain medications, and phenothiazine tranquilizers) or with tricyclic antidepressants can cause extreme fatigue or drowsiness.


Monoamine oxidase (MAO) inhibitors (isocarboxazid, pargyline, phenelzine, and tranylcypromine) can increase the side effects of this medication. At least 14 days should separate the use of this drug and the use of an MAO inhibitor.

Warnings :
Be sure to tell your doctor about unusual or allergic reactions you have had to any medications, especially to diphenhydramine or to any other antihistamine (such as astemizole, azatadine, brompheniramine, carbinoxamine, chlorpheniramine, clemastine, cyproheptadine, dexchlorpheniramine, dimenhydrinate, doxylamine, hydroxyzine, phenindamine, promethazine, pyrilamine, terfenadine, trimeprazine, tripelennamine, and triprolidine).


Tell your doctor if you now have or ever had asthma, blood vessel disease, glaucoma, high blood pressure, kidney disease, peptic ulcers, enlarged prostate gland, or thyroid disease.

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