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Dexamethasone (Systemic)

November 10th 2006 01:50
Dexamethasone belongs to a group of drugs known as adrenocorticosteroids (or cortisonelike medications). Your adrenal glands naturally produce certain cortisonelike chemicals. These chemicals are involved in various regulatory processes in the body (such as those involving fluid balance, temperature, and the reaction to inflammation).

Dexamethasone is used to treat a variety of disorders, including endocrine and rheumatic disorders; asthma; blood diseases; certain types of cancer; eye disorders; gastrointestinal disturbances, such as ulcerative colitis; respiratory diseases; and inflammations such as arthritis, dermatitis, and poison ivy. How dexamethasone acts to relieve these disorders is not completely understood.


Treatment :
To prevent stomach irritation, take dexamethasone with food or milk.

If you are taking only one dose of this medication each day, try to take it before 9:00 in the morning. This will mimic the body's normal production of this type of chemical.

Measure the elixir and solution with a specially designed 5-mL measuring spoon, not an ordinary kitchen teaspoon. The concentrate may be diluted in juice, other liquids, or semisolid foods like applesauce.

Interactions :
Dexamethasone interacts with several other types of drugs:

Alcohol, aspirin, and anti-inflammatory medications (such as diclofenac, diflunisal, fenoprofen, flurbiprofen, ibuprofen, indomethacin, naproxen, piroxicam, sulindac, and tolmetin) aggravate the stomach problems that may occur with use of this medication.


The dosage of oral anticoagulants (blood thinners, such as warfarin), oral antidiabetic drugs, or insulin may need to be altered when this medication is started or stopped.

Warnings :

Tell your doctor about unusual or allergic reactions you have had to any medications, especially to dexamethasone or other adrenocorticosteroids (such as alclometasone, amcinonide, betamethasone, clobetasol, clocortolone, cortisone, desonide, desoximetasone, diflorasone, flumethasone, fluocinolone, fluocinonide, fluorometholone, flurandrenolide, halcinonide, hydrocortisone, methylprednisolone, paramethasone, prednisolone, prednisone, and triamcinolone).


Tell your doctor if you now have or ever had bone disease of any sort, diabetes mellitus, emotional instability, glaucoma, fungal infections, heart disease, high blood pressure, high cholesterol levels, myasthenia gravis, peptic ulcers, osteoporosis, thyroid disease, tuberculosis, ulcerative colitis, kidney disease, or liver disease.


If you are using dexamethasone for longer than a week, you may need to receive higher doses if you are subjected to stress, such as serious infections, injury, or surgery. Discuss this with your doctor.
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